Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13324052 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1POLBHIF1A | |
| SCHEMBL17775012 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1POLBTSHR | |
| SCHEMBL9474505 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1POLBTSHR | |
| SCHEMBL9485569 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1POLBTSHR | |
| SCHEMBL29236632 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1POLBTSHR | |
| SCHEMBL17735454 | 0.84 | KMT2A (0.52) | ALDH1A1MAPTNPSR1TSHRRAB9A | |
| SCHEMBL7440818 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1POLBHIF1A | |
| SCHEMBL3199271 | 0.80 | GRM5 (0.49) | ALDH1A1MAPTNPSR1RAB9A | |
| SCHEMBL7347524 | 0.77 | ALDH1A1 (0.60) | ALDH1A1POLBHTR1ATSHRRAB9A | |
| SCHEMBL17267477 | 0.76 | HDAC7 (0.64) | ALDH1A1MAPTNPSR1DRD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130193-A1 | PRODUCTION METHOD FOR OPTICALLY ACTIVE ALCOHOL COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20160130193-A1 | PRODUCTION METHOD FOR OPTICALLY ACTIVE ALCOHOL COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130193-A1 | PRODUCTION METHOD FOR OPTICALLY ACTIVE ALCOHOL COMPOUND | ADH1C, ADH1A, ADH5 | ALDH1A1 82/4885MAPT 3963/4885NPSR1 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.