Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17738776 | 0.81 | ADRB1 (0.41) | — | |
| SCHEMBL5569781 | 0.73 | NR1H4 (0.41) | LATS1HDAC1 | |
| SCHEMBL17738256 | 0.70 | LATS1 (0.35) | LATS1HDAC1 | |
| SCHEMBL17739677 | 0.69 | LATS1 (0.34) | LATS1HDAC1 | |
| SCHEMBL17738267 | 0.68 | ADRB1 (0.38) | — | |
| SCHEMBL17738234 | 0.66 | LATS1 (0.34) | LATS1 | |
| SCHEMBL31687242 | 0.65 | IDO1 (0.44) | LATS1CDK1CDK4CCNB1CCNA2 | |
| SCHEMBL17731749 | 0.65 | IDO1 (0.44) | LATS1CDK1CDK4CCNB1CCNA2 | |
| SCHEMBL6023940 | 0.63 | ADRA2C (0.49) | LATS1HDAC1 | |
| SCHEMBL17513734 | 0.62 | ADRB1 (0.55) | CDK1CDK4CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016071293-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2016-05-12 | — | — | WO | disclosed |