Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023940 | 0.80 | ADRA2C (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17738256 | 0.79 | LATS1 (0.35) | LATS1POLBHDAC1PRKCQ | |
| SCHEMBL17513734 | 0.76 | ADRB1 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL6367433 | 0.75 | ADRB1 (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5567965 | 0.73 | ALDH1A1 (0.52) | NR1H4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5567969 | 0.73 | ALDH1A1 (0.52) | NR1H4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5569136 | 0.73 | ALDH1A1 (0.52) | NR1H4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15770057 | 0.73 | LATS1 (0.55) | LATS1HDAC1PRKCQMAPT | |
| SCHEMBL17739338 | 0.73 | LATS1 (0.33) | LATS1HDAC1 | |
| SCHEMBL17739677 | 0.72 | LATS1 (0.34) | LATS1HDAC1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458689-B1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-04-11 | — | — | EP | disclosed |
| US-7067501-B2 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2005-08-04 | — | — | US | disclosed |
| EP-1458689-A1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053942-A1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | SLC1A5, SLC6A7, SLC6A19 | NR1H4 241/4885HTR3E 1015/4885HTR3B 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.