Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17739040 | 0.83 | HDAC1 (0.40) | ADRA2CHDAC1KEAP1GAAMEN1 | |
| SCHEMBL17739006 | 0.82 | HDAC1 (0.40) | ADRA2CHDAC1KEAP1GAAMEN1 | |
| SCHEMBL15770057 | 0.80 | LATS1 (0.55) | HDAC1LATS1PRKCQCSNK1EMAPT | |
| SCHEMBL5569781 | 0.80 | NR1H4 (0.41) | ADRA2CHDAC1GAALATS1PRKCQ | |
| SCHEMBL20139950 | 0.78 | DRD2 (0.40) | HDAC1LATS1ADRB1CSNK1EKDM4E | |
| SCHEMBL19035611 | 0.76 | HTR3E (0.52) | HDAC1MEN1USP2KMT2ALATS1 | |
| SCHEMBL16580827 | 0.73 | MAPT (0.46) | ADRA2CHDAC1GAAMEN1USP2 | |
| SCHEMBL532010 | 0.73 | KEAP1 (0.64) | ADRA2CKEAP1GAAMEN1USP2 | |
| Hydrochloric Acid SCHEMBL4684126 | 0.72 | KEAP1 (0.62) | ADRA2CKEAP1GAAMEN1USP2 | |
| SCHEMBL293148 | 0.71 | DRD2 (0.43) | HDAC1ADRB1KDM4EHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7067501-B2 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | SLC1A5, SLC6A7, SLC6A19 | ADRA2C 1260/4885HDAC1 4191/4885KEAP1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.