Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17742302 | 1.00 | RXRA (0.60) | RXRARXRBRXRGMMP2HSD17B10 | |
| SCHEMBL17891642 | 0.89 | RXRA (0.77) | RXRARXRBRXRGMMP2HSD17B10 | |
| SCHEMBL17891657 | 0.89 | RXRA (0.77) | RXRARXRBRXRGMMP2HSD17B10 | |
| SCHEMBL17891641 | 0.89 | RXRA (0.77) | RXRARXRBRXRGMMP2HSD17B10 | |
| SCHEMBL31390163 | 0.88 | RXRA (0.78) | RXRARXRBRXRGMMP2HSD17B10 | |
| Isopimaric Acid SCHEMBL12732275 | 0.75 | RXRA (1.00) | RXRARXRBRXRGMMP2HSD17B10 | |
| Isopimaric Acid SCHEMBL15339339 | 0.75 | RXRA (1.00) | RXRARXRBRXRGMMP2HSD17B10 | |
| Isopimaric Acid SCHEMBL15744757 | 0.75 | RXRA (1.00) | RXRARXRBRXRGMMP2HSD17B10 | |
| Isopimaric Acid SCHEMBL4549113 | 0.75 | RXRA (1.00) | RXRARXRBRXRGMMP2HSD17B10 | |
| Isopimaric Acid SCHEMBL234276 | 0.75 | RXRA (1.00) | RXRARXRBRXRGMMP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| WO-2016073750-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-12 | — | — | WO | disclosed |