Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.77 |
| ▸ | RXRB | P28702 | 1/20 | 0.77 |
| ▸ | RXRG | P48443 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891641 | 1.00 | RXRA (0.77) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| SCHEMBL17891642 | 1.00 | RXRA (0.77) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| SCHEMBL17742302 | 0.89 | RXRA (0.60) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| SCHEMBL17742300 | 0.89 | RXRA (0.60) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL234276 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL15744757 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL15339339 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL12732275 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL4549113 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 | |
| Isopimaric Acid SCHEMBL15744755 | 0.87 | RXRA (1.00) | RXRARXRBRXRGHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH | 2018-05-10 | — | — | US | disclosed |
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194343-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | RXRA 785/4885RXRB 589/4885RXRG 898/4885 |
| US-20180127447-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | INF2, AFF2, KRAS | RXRA 785/4885RXRB 589/4885RXRG 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.