Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918973 | 0.86 | GAA (0.50) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL3972997 | 0.85 | KDM4E (0.63) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL17742904 | 0.84 | LCK (0.46) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL1920431 | 0.83 | CFTR (0.46) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL11065578 | 0.83 | KDM4E (0.52) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL30280800 | 0.83 | CFTR (0.46) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL857614 | 0.81 | KDM4E (0.74) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL8331820 | 0.81 | GAA (0.53) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL13468054 | 0.80 | KDM4E (0.49) | KDM4EPOLBALDH1A1HPGDKMT2A | |
| SCHEMBL1764082 | 0.80 | CA12 (0.46) | KDM4EPOLBALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016074566-A1 | GLUCOSIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | 镇江新元素医药科技有限公司 | 2016-05-19 | — | — | WO | disclosed |
| WO-2016070740-A1 | A CLASS OF NEW TYPE SGLT2 INHIBITOR COMPOUND AND A PHARMACEUTICAL COMPOSITION THEREOF | 镇江新元素医药科技有限公司 | 2016-05-12 | — | — | WO | disclosed |