Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16117940 | 0.86 | GAA (0.61) | GAAKDM4EPOLBHPGDHTT | |
| SCHEMBL25260035 | 0.84 | ALDH1A1 (0.46) | KDM4EHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL2849661 | 0.84 | CFTR (0.45) | GAAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL2476221 | 0.84 | GAA (0.62) | GAAKDM4EPOLBHPGDHTT | |
| SCHEMBL24625174 | 0.82 | KDM4E (0.41) | GAAKDM4EPOLBHPGDHTT | |
| SCHEMBL17239556 | 0.81 | CFTR (0.43) | GAAHPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7948445 | 0.81 | NR4A2 (0.46) | GAAKDM4EPOLBHTTALDH1A1 | |
| SCHEMBL17742903 | 0.81 | KDM4E (0.47) | GAAKDM4EPOLBHPGDHTT | |
| SCHEMBL27808161 | 0.80 | GAA (0.57) | GAAKDM4EPOLBHPGDHTT | |
| SCHEMBL11317879 | 0.80 | GAA (0.72) | GAAKDM4EPOLBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856574-A | ANTIISCHEMIC AGENTS; ANTIARRTHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |