Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063305 | 0.86 | ADRA2A (0.41) | TSHR | |
| SCHEMBL8228214 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2TSHRMEN1KMT2A | |
| SCHEMBL11346927 | 0.84 | PNMT (0.38) | TSHRSLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL4950480 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2TSHRMEN1KMT2A | |
| SCHEMBL29573380 | 0.83 | CYSLTR2 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL8723703 | 0.83 | CYSLTR2 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL27725414 | 0.81 | CHRM2 (0.34) | — | |
| SCHEMBL11358599 | 0.81 | ADRA2C (0.45) | GABRA1GABRB2TSHRCYP2D6SLC6A2 | |
| SCHEMBL9717390 | 0.79 | TSHR (0.33) | GABRA1GABRB2TSHRHTTMEN1 | |
| SCHEMBL28555953 | 0.78 | HSPA5 (0.53) | GABRA1GABRB2TSHRCYP2D6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166579-A1 | COMPACT OR FREE ANHYDROUS POWDER BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT | L'Oréal (FR) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016005248-A1 | COMPACT OR FREE ANHYDROUS POWDER BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT | L'OREAL (FR) | 2016-01-14 | — | — | WO | disclosed |
| US-8754028-B2 | Perfume systems | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| US-8357649-B2 | Delivery particle | THE PROCTER & GAMBLE COMPANY (US) | 2013-01-22 | — | — | US | disclosed |
| US-20110107524-A1 | DELIVERY PARTICLE | THE PROCTER & GAMBLE COMPANY | 2011-05-12 | — | — | US | disclosed |
| US-20100152083-A1 | Perfume Systems | PROCTER & GAMBLE COMPANY, THE | 2010-06-17 | — | — | US | disclosed |
| CN-101448798-A | Compounds and methods for modulating FXR | LILLY CO ELI (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-100424100-C | Beta-ketimine vanadium olefinic polymerization catalyst, and its preparing method and use | CHANGCHUN APPLIED CHEMISTRY (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-100395234-C | Novel CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2008-06-18 | — | — | CN | disclosed |
| CN-101198594-A | Process for the production of intermadiates for the preparation of tricyclic benzimidazoles | NYCOMED GMBH (DE) | 2008-06-11 | — | — | CN | disclosed |
| CN-101012193-A | Novel CB 1 receptour inverse agonists | HOFFMANN LA ROCHE (CH) | 2007-08-08 | — | — | CN | disclosed |
| CN-1850869-A | Beta-ketimine vanadium olefinic polymerization catalyst, and its preparing method and use | CHANGCHUN APPLIED CHEMISTRY (CN) | 2006-10-25 | — | — | CN | disclosed |
| CN-1735593-A | Novel CB1 receptor inverse agonists | HOFFMANN LA ROCHE (CH) | 2006-02-15 | — | — | CN | disclosed |
| US-5677299-A | VASOPRESSIN OR OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5498609-A | Benzoazepinyl compounds as oxytocin and vasopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0612319-A1 | BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| CN-1090576-A | Benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 1994-08-10 | — | — | CN | disclosed |
| WO-1994004525-A1 | BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-03-03 | — | — | WO | disclosed |