SCHEMBL17744853

SCHEMBL17744853

Nc1ccc(C(=O)Oc2ccccc2-c2ccc(C(=O)O)c(N)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
PPM1B O75688 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KMT2A Q03164 4/20 0.41
SELL P14151 1/20 0.41
SELP P16109 1/20 0.41
MCL1 Q07820 1/20 0.40
FEN1 P39748 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HSD17B10 Q99714 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
TOP1 P11387 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744843 0.88 ESR1 (0.44) ESR1ESR2PPM1BSLC6A3KMT2A
SCHEMBL13205873 0.79 DHODH (0.54) PPM1BMCL1KDM4EHSD17B10ALDH1A1
SCHEMBL17744885 0.79 SLC6A3 (0.46) ESR1ESR2SLC6A3KMT2ASMN1; SMN2
SCHEMBL17744875 0.78 SLC6A3 (0.48) ESR1ESR2SLC6A3KMT2ASMN1; SMN2
SCHEMBL17744878 0.78 KMT2A (0.44) ESR1ESR2SLC6A3KMT2ASMN1; SMN2
SCHEMBL30343057 0.78 KDM4E (0.58) ESR1ESR2SLC6A3KMT2ASMN1; SMN2
SCHEMBL28771794 0.76 RXRA (0.50) ESR1ESR2SLC6A3KMT2ASELL
SCHEMBL2569649 0.75 DRD1 (0.49) PPM1BKMT2AMCL1FEN1MAPT
SCHEMBL29015053 0.75 ALDH1A1 (0.60) ESR1ESR2SLC6A3KMT2AMCL1
SCHEMBL6442018 0.75 ESR2 (0.47) ESR1ESR2SLC6A3KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed