Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.47 |
| ▸ | ESR1 | P03372 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879378 | 0.82 | ESR1 (0.60) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL29015053 | 0.78 | ALDH1A1 (0.60) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL8001713 | 0.77 | ESR1 (0.54) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL107412 | 0.76 | MAPT (0.47) | ESR2ESR1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5710320 | 0.76 | MEN1 (0.52) | ESR2KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL17744875 | 0.75 | SLC6A3 (0.48) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL27660356 | 0.75 | ESR1 (0.57) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL30343057 | 0.75 | KDM4E (0.58) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL17744853 | 0.75 | ESR1 (0.46) | ESR2ESR1KMT2AMAPTHSD17B10 | |
| SCHEMBL29266652 | 0.75 | ESR1 (0.46) | ESR2ESR1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1593713-A1 | Polymerizable dichromophoric dichroic azo dyes | Rolic AG (CH) | 2005-11-09 | — | — | EP | disclosed |