Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.54 |
| ▸ | CPA3 | P15088 | 2/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 5/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747737 | 1.00 | CPA1 (0.54) | CPA1CPA3CPB1CPB2MMP3 | |
| SCHEMBL17747692 | 0.88 | MMP3 (0.47) | CPA1CPA3CPB1CPB2MMP3 | |
| SCHEMBL8609583 | 0.84 | MMP3 (0.53) | MMP3MMP1MMP8MMP9SLC1A1 | |
| SCHEMBL17747715 | 0.84 | MMP3 (0.46) | CPA1CPA3CPB1CPB2MMP3 | |
| SCHEMBL17747713 | 0.84 | MMP3 (0.46) | CPA1CPA3CPB1CPB2MMP3 | |
| SCHEMBL17747711 | 0.84 | MMP3 (0.46) | CPA1CPA3CPB1CPB2MMP3 | |
| SCHEMBL15684087 | 0.84 | L3MBTL1 (0.51) | MMP3MMP1MMP8MMP9SLC1A1 | |
| SCHEMBL14243701 | 0.84 | L3MBTL1 (0.51) | MMP3MMP1MMP8MMP9SLC1A1 | |
| SCHEMBL27637199 | 0.83 | MMP12 (0.52) | MMP3MMP1MMP8MMP9FOLH1 | |
| SCHEMBL27637198 | 0.83 | MMP12 (0.52) | MMP3MMP1MMP8MMP9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | CPA1 2403/4885CPA3 1395/4885CPB1 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.