Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748347 | 1.00 | NOD1 (0.43) | NOD1FNTAFNTBPGGT1BC3AR1 | |
| SCHEMBL29415209 | 0.93 | NOD1 (0.43) | NOD1FNTAFNTBPGGT1BC3AR1 | |
| SCHEMBL30516169 | 0.92 | NOD1 (0.41) | NOD1FNTAFNTBPGGT1BNPY4R | |
| SCHEMBL27632323 | 0.91 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BC3AR1 | |
| SCHEMBL27632326 | 0.91 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1BC3AR1 | |
| SCHEMBL30662552 | 0.91 | NOD1 (0.42) | NOD1FNTAFNTBPGGT1BC3AR1 | |
| SCHEMBL18378106 | 0.90 | NOD1 (0.43) | NOD1FNTAFNTBPGGT1BFOLH1 | |
| SCHEMBL18378107 | 0.90 | NOD1 (0.43) | NOD1FNTAFNTBPGGT1BFOLH1 | |
| SCHEMBL23391087 | 0.90 | PTGS1 (0.41) | NOD1FNTAFNTBPGGT1BNPY4R | |
| SCHEMBL23391080 | 0.90 | PTGS1 (0.41) | NOD1FNTAFNTBPGGT1BNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218390-A2 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | Amunix Operating Inc. (US) | 2017-09-20 | — | — | EP | claimed |
| WO-2016077505-A2 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX OPERATING INC. (US) | 2016-05-19 | — | — | WO | claimed |
| US-20180125988-A1 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX OPERATING INC. | 2018-05-10 | — | — | US | disclosed |
| EP-3218390-A2 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | Amunix Operating Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016077505-A2 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX OPERATING INC. (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125988-A1 | TARGETED XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | ADAM33, ADAM12, PTMS | NOD1 1740/4885FNTA 1106/4885FNTB 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.