SCHEMBL29415209

SCHEMBL29415209

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](N)CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 6/20 0.43
▸ FNTA P49354 2/20 0.40
▸ FNTB P49356 2/20 0.40
▸ PGGT1B P53609 1/20 0.40
▸ C3AR1 Q16581 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ GSTK1 Q9Y2Q3 1/20 0.38
▸ NPY4R P50391 7/20 0.38
▸ NPY1R P25929 5/20 0.38
▸ NPY2R P49146 5/20 0.38
▸ NPY5R Q15761 5/20 0.38
▸ GNPAT O15228 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30662552 0.98 NOD1 (0.42) NOD1FNTAFNTBPGGT1BC3AR1
SCHEMBL29880860 0.93 GNPAT (0.41) NOD1C3AR1PTGS1GSTK1NPY4R
SCHEMBL17748346 0.93 NOD1 (0.43) NOD1FNTAFNTBPGGT1BC3AR1
SCHEMBL17748347 0.93 NOD1 (0.43) NOD1FNTAFNTBPGGT1BC3AR1
SCHEMBL27632326 0.91 NOD1 (0.51) NOD1FNTAFNTBPGGT1BC3AR1
SCHEMBL27632323 0.91 NOD1 (0.51) NOD1FNTAFNTBPGGT1BC3AR1
SCHEMBL29942412 0.91 NPY4R (0.41) NOD1PTGS1GSTK1NPY4RNPY1R
SCHEMBL31099287 0.91 NOD1 (0.45) NOD1FNTAFNTBPGGT1BNPY4R
SCHEMBL2068782 0.91 GNPAT (0.40) NOD1FNTAFNTBPGGT1BNPY4R
SCHEMBL9440021 0.90 NOD1 (0.43) NOD1FNTAFNTBPGGT1BPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536265-A2 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Jenius Pharma, LLC (US) 2025-04-16 — — EP claimed
US-20240384007-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION NOVARTIS AG (CH) 2024-11-21 — — US claimed
EP-4389216-A2 PEPTIDE COMPOSITIONS AND THERAPEUTIC USES Allegro Pharmaceuticals, LLC (US) 2024-06-26 — — EP claimed
US-11999802-B2 Compositions and methods for selective protein degradation NOVARTIS AG (CH) 2024-06-04 — — US claimed
US-20240132542-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Allegro Pharmaceuticals, LLC 2024-04-25 — — US claimed
WO-2023239716-A2 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Allegro Pharmaceuticals, LLC (US) 2023-12-14 — — WO claimed
EP-4219721-A2 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION Novartis AG (CH) 2023-08-02 — — EP claimed
US-20230174933-A1 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS NOVARTIS AG (CH) 2023-06-08 — — US claimed
US-20230071283-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION Payne, Aimee S. (US) 2023-03-09 — — US claimed
EP-3443096-B1 COMPOSITIONS AND METHODS FOR SELECTIVE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS NOVARTIS AG (CH) 2023-03-01 — — EP claimed
EP-4110377-A2 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS Novartis AG (CH) 2023-01-04 — — EP claimed
CN-115397460-A Methods of making cells expressing chimeric antigen receptors 诺华股份有限公司 2022-11-25 — — CN claimed
CN-115340996-A Co-expression method of multi-subunit protein by using specific enzyme cutting site 态创生物科技(广州)有限公司 2022-11-15 — — CN claimed
CN-111494642-B Self-assembly material for in-situ construction of artificial extracellular matrix and preparation method and application thereof 国家纳米科学中心 2022-10-14 — — CN claimed
US-20220307053-A1 REGULATABLE EXPRESSION SYSTEMS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2022-09-29 — — US claimed
US-20220175667-A1 Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices THE JOHNS HOPKINS UNIVERSITY 2022-06-09 — — US claimed
EP-4004213-A1 REGULATABLE EXPRESSION SYSTEMS Novartis AG (CH) 2022-06-01 — — EP claimed
CN-114174514-A Adjustable expression system 诺华股份有限公司 2022-03-11 — — CN claimed
CN-110627912-B Bionic fiber network antibody self-assembly material and preparation method and application thereof 国家纳米科学中心 2022-03-08 — — CN claimed
US-12612638-B2 Fusion constructs to express biopharmaceutical polypeptides in cyanobacteria THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-28 — — US disclosed
US-20250382328-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS JENIUS PHARMA LLC (US) 2025-12-18 — — US disclosed
US-12454549-B2 Treatments for diseases and disorders that involve oxidative stress JENIUS PHARMA, LLC (US) 2025-10-28 — — US disclosed
CN-120137971-A Adjustable expression system 诺华股份有限公司 2025-06-13 — — CN disclosed
US-20250129342-A1 ALPHAVIRUS REPLICON PARTICLE VLP THERAPEUTICS, INC. (US) 2025-04-24 — — US disclosed
EP-4536265-A2 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Jenius Pharma, LLC (US) 2025-04-16 — — EP disclosed
US-12227770-B2 Alphavirus replicon particle VLP THERAPEUTICS, INC. (US) 2025-02-18 — — US disclosed
US-20240384007-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION NOVARTIS AG (CH) 2024-11-21 — — US disclosed
CN-118388659-A Method for rapidly preparing multiple MHC-antigen peptide tetramers and application thereof 苏州系统医学研究所 2024-07-26 — — CN disclosed
EP-4389216-A2 PEPTIDE COMPOSITIONS AND THERAPEUTIC USES Allegro Pharmaceuticals, LLC (US) 2024-06-26 — — EP disclosed
US-11999802-B2 Compositions and methods for selective protein degradation NOVARTIS AG (CH) 2024-06-04 — — US disclosed
WO-2023239716-A2 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Allegro Pharmaceuticals, LLC (US) 2023-12-14 — — WO disclosed
CN-111019927-B Recombinant plasmid for expressing TEV protein, recombinant engineering bacterium and method for preparing and purifying TEV protein 重庆艾力彼生物科技有限公司 2023-10-13 — — CN disclosed
EP-4219721-A2 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION Novartis AG (CH) 2023-08-02 — — EP disclosed
US-20230174933-A1 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS NOVARTIS AG (CH) 2023-06-08 — — US disclosed
CN-110938151-B Fusion protein for expressing parathyroid hormone PTH, recombinant plasmid and recombinant engineering bacteria 重庆艾力彼生物科技有限公司 2023-03-17 — — CN disclosed
US-20230071283-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION Payne, Aimee S. (US) 2023-03-09 — — US disclosed
US-11597727-B2 Inhibitors of integrin alpha 2 beta 1 and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-07 — — US disclosed
EP-3443096-B1 COMPOSITIONS AND METHODS FOR SELECTIVE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS NOVARTIS AG (CH) 2023-03-01 — — EP disclosed
US-20230056486-A1 METHODS OF TREATING NEUROLOGICAL DISORDERS ENCLEAR THERAPIES INC (US) 2023-02-23 — — US disclosed
EP-4110377-A2 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS Novartis AG (CH) 2023-01-04 — — EP disclosed
CN-115397460-A Methods of making cells expressing chimeric antigen receptors 诺华股份有限公司 2022-11-25 — — CN disclosed
US-20220372499-A1 FUSION CONSTRUCTS TO EXPRESS BIOPHARMACEUTICAL POLYPEPTIDES IN CYANOBACTERIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-11-24 — — US disclosed
CN-115340996-A Co-expression method of multi-subunit protein by using specific enzyme cutting site 态创生物科技(广州)有限公司 2022-11-15 — — CN disclosed
CN-111494642-B Self-assembly material for in-situ construction of artificial extracellular matrix and preparation method and application thereof 国家纳米科学中心 2022-10-14 — — CN disclosed
US-20220307053-A1 REGULATABLE EXPRESSION SYSTEMS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2022-09-29 — — US disclosed
US-11419921-B2 Methods of treating neurological disorders ENCLEAR THERAPIES, INC. (US) 2022-08-23 — — US disclosed
US-20220251152-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION NOVARTIS AG (CH) 2022-08-11 — — US disclosed
EP-4028529-A1 FUSION CONSTRUCTS TO EXPRESS BIOPHARMACEUTICAL POLYPEPTIDES IN CYANOBACTERIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-07-20 — — EP disclosed
US-20220175667-A1 Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices THE JOHNS HOPKINS UNIVERSITY 2022-06-09 — — US disclosed
EP-4004213-A1 REGULATABLE EXPRESSION SYSTEMS Novartis AG (CH) 2022-06-01 — — EP disclosed
CN-114174514-A Adjustable expression system 诺华股份有限公司 2022-03-11 — — CN disclosed
CN-110627912-B Bionic fiber network antibody self-assembly material and preparation method and application thereof 国家纳米科学中心 2022-03-08 — — CN disclosed
CN-110627912-B Bionic fiber network antibody self-assembly material and preparation method and application thereof 国家纳米科学中心 2022-03-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230071283-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION BCL6, BCL3, BCL6B NOD1 3517/4885FNTA 2520/4885FNTB 1785/4885
US-11597727-B2 Inhibitors of integrin alpha 2 beta 1 and methods of use ITGB1, ITGB2, ITGA2 NOD1 3250/4885FNTA 2305/4885FNTB 318/4885
US-20240132542-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS GPX4, GPX1, TXNRD2 NOD1 3637/4885FNTA 3181/4885FNTB 3703/4885
US-12612638-B2 Fusion constructs to express biopharmaceutical polypeptides in cyanobacteria CPB2, IRF2BP2, SPPL2B NOD1 3240/4885FNTA 789/4885FNTB 53/4885
US-20240384007-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION CRBN, RPS27A, COPB1 NOD1 3242/4885FNTA 2885/4885FNTB 2489/4885
US-20220175667-A1 Extracellular Matrices, Uses Thereof, and Methods of Making Extracellular Matrices EPCAM, CD44, MATR3 NOD1 3974/4885FNTA 1053/4885FNTB 2575/4885
US-12454549-B2 Treatments for diseases and disorders that involve oxidative stress GPX4, GPX1, TXNRD2 NOD1 3637/4885FNTA 3181/4885FNTB 3703/4885
US-20250382328-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS GPX4, GPX1, TXNRD2 NOD1 3637/4885FNTA 3181/4885FNTB 3703/4885
US-11999802-B2 Compositions and methods for selective protein degradation CRBN, RPS27A, COPB1 NOD1 3242/4885FNTA 2885/4885FNTB 2489/4885
US-20230174933-A1 METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS HAVCR2, MICA, CD74 NOD1 2550/4885FNTA 1677/4885FNTB 1513/4885
US-20220251152-A1 COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION RPS27A, PSMG3, PREP NOD1 3072/4885FNTA 893/4885FNTB 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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