Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 12/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775413 | 0.81 | MALT1 (0.48) | TLR9MALT1SUV39H2ALKKIT | |
| SCHEMBL1777001 | 0.76 | KIT (0.42) | TLR9TLR7KIT | |
| SCHEMBL1776091 | 0.73 | TLR9 (0.45) | TLR9TLR7ALKKIT | |
| SCHEMBL1775510 | 0.73 | ACHE (0.48) | TLR9TLR7ALKKIT | |
| SCHEMBL1774426 | 0.73 | GBA1 (0.43) | TLR9TLR7KIT | |
| SCHEMBL5063132 | 0.73 | KIT (0.42) | TLR9TLR7KIT | |
| SCHEMBL1776820 | 0.73 | MEN1 (0.47) | TLR9TLR7KIT | |
| SCHEMBL1775118 | 0.73 | KIT (0.48) | KIT | |
| SCHEMBL1776534 | 0.72 | MAPT (0.39) | TLR9TLR7KIT | |
| Hydrochloric Acid SCHEMBL6425045 | 0.72 | HTR6 (0.37) | MALT1SUV39H2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | disclosed |
| EP-1897881-A2 | Compounds useful for the treatment of obesity, type II diabetes and CNS disorders | Biovitrum AB (publ) (SE) | 2008-03-12 | — | — | EP | disclosed |
| US-20040024210-A1 | New compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024210-A1 | New compounds | SULT1E1, SULT2A1, SULT1A1 | TLR9 3686/4885MALT1 2170/4885SUV39H2 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.