Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16064965 | 0.90 | HTT (0.60) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL17702625 | 0.81 | KMT2A (0.70) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL16064957 | 0.80 | HTT (0.54) | HTTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL12422575 | 0.79 | KDM4E (0.58) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL20999491 | 0.79 | KDM4E (0.63) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL27004615 | 0.78 | HTT (0.62) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL11513574 | 0.77 | ALDH1A1 (0.57) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL17703651 | 0.77 | KDM4E (0.57) | HTTKDM4EEPHX2KMT2AMEN1 | |
| SCHEMBL19426816 | 0.76 | KDM4E (0.59) | HTTKDM4EEPHX2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11516217 | 0.76 | ALDH1A1 (0.59) | HTTKDM4EEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160136233-A1 | NOVEL CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION | ENANTA PHARM INC (US) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160136233-A1 | NOVEL CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION | HAVCR2, CHP1, MAVS | HTT 2563/4885KDM4E 4305/4885EPHX2 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.