Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755397 | 0.90 | HTT (0.57) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL18433968 | 0.83 | KDM4E (0.41) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL16064957 | 0.82 | HTT (0.54) | HTTKDM4EKMT2AMEN1LMNA | |
| SCHEMBL28334704 | 0.78 | KDM4E (0.68) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL18433716 | 0.77 | KDM4E (0.38) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL17702625 | 0.77 | KMT2A (0.70) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL8655345 | 0.77 | KDM4E (0.66) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL13873443 | 0.77 | HTT (0.66) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL22005490 | 0.76 | KDM4E (0.60) | HTTKDM4EKMT2AMEN1EPHX2 | |
| SCHEMBL6891227 | 0.76 | ALDH1A1 (0.62) | HTTKDM4EKMT2AMEN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9883997-B2 | Cosmetic compositions with tricyclodecane amides | CONOPCO, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9840466-B2 | Process of making adamantanamides | CONOPCO, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| EP-2969026-B1 | COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES | UNILEVER PLC (GB) | 2017-11-01 | — | — | EP | disclosed |
| US-9775793-B2 | Prolonged delivery of certain fragrance components from personal care compositions | CONOPCO, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| EP-3080086-B1 | PROCESS OF MAKING ADAMANTANAMIDES | UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) | 2017-07-05 | — | — | EP | disclosed |
| US-9682028-B2 | Personal care photoprotective compositions with tricyclodecane amides | CONOPCO, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20170029375-A1 | PROCESS OF MAKING ADAMANTANAMIDES | CONOPCO, INC., D/B/A UNILEVER (US) | 2017-02-02 | — | — | US | disclosed |
| EP-2968082-B1 | PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS | UNILEVER PLC (GB) | 2017-02-01 | — | — | EP | disclosed |
| US-20160045419-A1 | PERSONAL CARE PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES | CONOPCO, INC., D/B/A UNILEVER (US) | 2016-02-18 | — | — | US | disclosed |
| US-20160015616-A1 | PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160008249-A1 | COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES | CONOPCO, INC., D/B/A UNILEVER (US) | 2016-01-14 | — | — | US | disclosed |
| WO-2015086428-A1 | PROCESS OF MAKING ADAMANTANAMIDES | UNILEVER PLC (GB) | 2015-06-18 | — | — | WO | disclosed |
| WO-2014139952-A2 | PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS | UNILEVER PLC (GB) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014139965-A1 | PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES | UNILEVER PLC (GB) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014139963-A1 | COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES | UNILEVER PLC (GB) | 2014-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015616-A1 | PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS | DPM1, DHCR24, POLR1C | HTT 2174/4885KDM4E 3863/4885KMT2A 3691/4885 |
| US-20160045419-A1 | PERSONAL CARE PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES | CUTA, ERCC1, ERCC5 | HTT 101/4885KDM4E 1411/4885KMT2A 2497/4885 |
| US-20160008249-A1 | COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES | CUTA, ACMSD, LAGE3 | HTT 1219/4885KDM4E 569/4885KMT2A 621/4885 |
| US-20170029375-A1 | PROCESS OF MAKING ADAMANTANAMIDES | APOBEC3G, APOBEC3A, APOBEC3B | HTT 1041/4885KDM4E 4025/4885KMT2A 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.