Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755791 | 0.89 | RORC (0.45) | RORC | |
| SCHEMBL17755785 | 0.87 | HPGD (0.41) | RORCEPHX2LMNAHPGD | |
| SCHEMBL17755781 | 0.87 | HPGD (0.41) | RORCEPHX2LMNAHPGD | |
| SCHEMBL17755779 | 0.82 | LMNA (0.44) | LMNAHPGD | |
| SCHEMBL17755774 | 0.76 | NPC1 (0.47) | LMNAHPGD | |
| SCHEMBL17755786 | 0.76 | RORC (0.45) | RORCLMNAHPGD | |
| SCHEMBL17755778 | 0.73 | LMNA (0.44) | LMNAHPGD | |
| SCHEMBL17755788 | 0.73 | ALDH1A1 (0.41) | EPHX2LMNAHPGD | |
| SCHEMBL17755770 | 0.68 | HPGD (0.49) | LMNAHPGD | |
| SCHEMBL17755766 | 0.68 | HPGD (0.49) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | RORC 233/4885EPHX2 3022/4885LMNA 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.