Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737312 | 0.71 | SMN1; SMN2 (0.32) | ALDH1A1KDM4EGAAMAPTAGTR1 | |
| SCHEMBL17755874 | 0.70 | GRIA1 (0.35) | — | |
| SCHEMBL17755900 | 0.66 | APAF1 (0.40) | ALDH1A1L3MBTL1APAF1 | |
| SCHEMBL3657281 | 0.65 | TRPA1 (0.42) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL16021532 | 0.65 | — | — | |
| SCHEMBL10720644 | 0.64 | MAPT (0.35) | ALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL2131959 | 0.63 | HCAR2 (0.39) | EPHX2ALDH1A1GAAEDNRA | |
| SCHEMBL7826668 | 0.63 | GAA (0.36) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL7030589 | 0.62 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1LPAR1LPAR3KDM4E | |
| SCHEMBL19240419 | 0.60 | POLB (0.46) | ALDH1A1L3MBTL1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | EPHX2 3022/4885ALDH1A1 560/4885L3MBTL1 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.