Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17756151 | 0.87 | PPARA (0.48) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL29447511 | 0.78 | LTA4H (0.57) | PPARALTA4HCTSSL3MBTL1PPARG | |
| SCHEMBL6293054 | 0.78 | L3MBTL1 (0.50) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL17762214 | 0.77 | CA1 (0.40) | CTSSL3MBTL1MAPT | |
| SCHEMBL486967 | 0.76 | L3MBTL1 (0.49) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL30598766 | 0.76 | L3MBTL1 (0.49) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL486968 | 0.76 | L3MBTL1 (0.49) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL7418511 | 0.75 | PPARA (0.48) | PPARALTA4HCTSSL3MBTL1PPARG | |
| SCHEMBL18939254 | 0.75 | L3MBTL1 (0.42) | PPARALTA4HCTSSL3MBTL1POLB | |
| SCHEMBL18964242 | 0.75 | L3MBTL1 (0.42) | PPARALTA4HCTSSL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | PPARA 661/4885LTA4H 2010/4885CTSS 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.