Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17756149 | 0.87 | PPARA (0.44) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL28494073 | 0.84 | CTSS (0.45) | CTSSMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6293054 | 0.82 | L3MBTL1 (0.50) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL486968 | 0.81 | L3MBTL1 (0.49) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL30598766 | 0.81 | L3MBTL1 (0.49) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL486967 | 0.81 | L3MBTL1 (0.49) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL12268042 | 0.81 | SLC1A3 (0.49) | CTSSPOLBMEN1KMT2A | |
| SCHEMBL22086824 | 0.81 | HTT (0.46) | PPARAMMEALDH1A1MEN1KMT2A | |
| SCHEMBL29447511 | 0.80 | LTA4H (0.57) | PPARAL3MBTL1PPARGLTA4HCTSS | |
| SCHEMBL7418511 | 0.80 | PPARA (0.48) | PPARAL3MBTL1PPARGLTA4HCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | PPARA 661/4885L3MBTL1 4739/4885PPARG 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.