Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200624 | 0.95 | IDO1 (0.58) | IDO1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1145617 | 0.77 | TAAR1 (0.60) | IDO1AGXTTAAR1 | |
| SCHEMBL63291 | 0.76 | IDO1 (0.47) | IDO1 | |
| SCHEMBL11258820 | 0.76 | ALDH1A1 (0.53) | IDO1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL61391 | 0.74 | IDO1 (1.00) | IDO1ALDH1A1CALM1TSHRAGXT | |
| SCHEMBL20865065 | 0.74 | ALDH1A1 (0.50) | IDO1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1621101 | 0.74 | DAO (0.53) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1742765 | 0.74 | ALDH1A1 (0.50) | IDO1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18769324 | 0.74 | GRIN2D (0.50) | IDO1ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5252553 | 0.72 | ALDH1A1 (0.65) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344005-B2 | Synthesis of cyclophanes for a self-assembly reaction | UNIVERSITY OF OREGON (US) | 2019-07-09 | — | — | US | disclosed |
| US-9790192-B2 | Synthesis of cyclophanes from a self-assembly reaction | UNIVERSITY OF OREGON (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | UNIVERSITY OF OREGON (US) | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344005-B2 | Synthesis of cyclophanes for a self-assembly reaction | TST, CTH, CBS | IDO1 1189/4885ALDH1A1 2325/4885GRIN2D 2918/4885 |
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | TST, CTH, CBS | IDO1 1121/4885ALDH1A1 2361/4885GRIN2D 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.