Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776084 | 1.00 | NR3C1 (0.70) | NR3C1NR3C2 | |
| SCHEMBL5521730 | 0.82 | NR3C1 (1.00) | NR3C1NR3C2 | |
| SCHEMBL5521600 | 0.82 | NR3C1 (1.00) | NR3C1NR3C2 | |
| SCHEMBL5518557 | 0.81 | NR3C1 (0.89) | NR3C1NR3C2 | |
| SCHEMBL4772164 | 0.79 | NR3C1 (0.69) | NR3C1NR3C2 | |
| SCHEMBL5524371 | 0.79 | NR3C2 (0.78) | NR3C1NR3C2 | |
| SCHEMBL4772156 | 0.79 | NR3C1 (0.69) | NR3C1NR3C2 | |
| SCHEMBL5519954 | 0.79 | NR3C1 (0.69) | NR3C1NR3C2 | |
| SCHEMBL303846 | 0.79 | NR3C1 (0.76) | NR3C1NR3C2 | |
| SCHEMBL5516517 | 0.78 | NR3C1 (0.80) | NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013185-B1 | NOVEL COMPOUNDS | GLAXO GROUP LTD (GB) | 2012-05-30 | — | — | EP | disclosed |
| US-8178573-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2012-05-15 | — | — | US | disclosed |
| US-7943651-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2011-05-17 | — | — | US | disclosed |
| US-20090111866-A1 | Novel Compounds | GLAXO WELLCOME HOUSE (GB) | 2009-04-30 | — | — | US | disclosed |
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | GLAXO GROUP LIMITED, A CORPORATION | 2008-08-28 | — | — | US | disclosed |
| EP-1896438-A1 | PHENYL-PYRAZOLE DERIVATIVES AS NON-STEROIDAL GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2008-03-12 | — | — | EP | disclosed |
| US-20070265326-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-11-15 | — | — | US | disclosed |
| WO-2007000334-A1 | PHENYL-PYRAZOLE DERIVATIVES AS NON-STEROIDAL GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207725-A1 | Phenyl-Pyrazole Derivatives as Non-Steroidal Glucocorticoid Receptor Ligands | NR3C1, NR3C2, NR5A1 | NR3C1 1/4885NR3C2 2/4885 |
| US-20070265326-A1 | NOVEL COMPOUNDS | CCL11, MRGPRX2, LTB4R2 | NR3C1 190/4885NR3C2 271/4885 |
| US-20090111866-A1 | Novel Compounds | CCL11, MRGPRX2, LTB4R2 | NR3C1 190/4885NR3C2 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.