SCHEMBL17759672

SCHEMBL17759672

c1ccc(-c2ccc(-n3c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5cccc(-c6ccccc6)c5)cc4c4c5c(ccc43)oc3ccccc35)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.37
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.34
PRKDC P78527 3/20 0.33
KMT2A Q03164 2/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
HSD17B10 Q99714 1/20 0.33
WNK1 Q9H4A3 1/20 0.32
EDNRB P24530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652808 1.00 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17760215 0.99 KDM4E (0.42) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17760017 0.99 KDM4E (0.42) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL19652944 0.98 PLA2G2A (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL19652730 0.96 L3MBTL1 (0.44) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17760770 0.96 L3MBTL1 (0.44) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL19652779 0.95 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17299942 0.94 L3MBTL1 (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24676318 0.94 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL24675445 0.94 KDM4E (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2021-09-28 US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 US disclosed
WO-2016076629-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same SOD1, TERT, TELO2 KDM4E 2736/4885ATM 3138/4885L3MBTL1 59/4885
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 KDM4E 2915/4885ATM 3046/4885L3MBTL1 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.