SCHEMBL1776

SCHEMBL1776

CC(=O)CCc1ccc(Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
PLAAT3 P53816 3/20 0.56
PLAAT5 Q96KN8 3/20 0.56
PLAAT2 Q9NWW9 3/20 0.56
PLAAT4 Q9UL19 3/20 0.56
HDAC1 Q13547 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
FFAR1 O14842 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CYP1A2 P05177 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134885 0.91 ALDH1A1 (0.53) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL13235754 0.89 FFAR1 (0.53) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL10912165 0.89 ALDH1A1 (0.77) ALDH1A1HDAC1FFAR1CYP1A2KDM4E
SCHEMBL2656163 0.88 HDAC3 (0.56) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL11241207 0.85 FFAR1 (0.75) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL9627289 0.85 MAOB (0.68) FFAR1NPC1MAOARAB9A
SCHEMBL11638133 0.84 HDAC3 (0.62) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL11565973 0.83 KMT2A (0.56) ALDH1A1HDAC1FFAR1MEN1KMT2A
SCHEMBL7328721 0.82 PLAAT3 (0.55) PLAAT3PLAAT5PLAAT2PLAAT4HDAC1
SCHEMBL7946947 0.82 TAAR1 (0.50) ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119571401-A Environment-friendly cyanide-free zincate galvanization brightening agent and preparation method thereof 苏州金蚂蚁精密钣金有限公司 2025-03-07 CN claimed
CN-115850151-A Schiff base analog compound and synthetic method thereof, PI3K kinase inhibitor and application thereof 成都普康生物科技有限公司 2023-03-28 CN claimed
CN-119571401-A Environment-friendly cyanide-free zincate galvanization brightening agent and preparation method thereof 苏州金蚂蚁精密钣金有限公司 2025-03-07 CN disclosed
CN-119120338-A Prostaglandin reductase and glucose dehydrogenase co-expression recombinant bacterium and application thereof 淮阴工学院 2024-12-13 CN disclosed
WO-2024050825-A1 COMPOUNDS AS MLKL INHIBITORS NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) 2024-03-14 WO disclosed
CN-111479806-B D-amino acid oxidase inhibitors and therapeutic uses thereof 心悦生医股份有限公司 2024-01-30 CN disclosed
US-20230339913-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS NURA BIO, INC. 2023-10-26 US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 US disclosed
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-09-12 US disclosed
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-0020173-B1 IMIDAZOLE GUANIDINES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1983-02-09 EP disclosed
US-4336261-A IMIDAZO/1,2A/PYRIDINE, HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1982-06-22 US disclosed
US-4252803-A HYPOTENSIVE AGENTS, ANALGESICS GLAXO GROUP LIMITED (GB) 1981-02-24 US disclosed
EP-0020173-A1 Imidazole guanidines, their preparation and compositions containing them MERCK & CO. INC. (US) 1980-12-10 EP disclosed
US-4220654-A Cyclic imidazole cyanoguanidines MERCK & CO., INC. (US) 1980-09-02 US disclosed
US-4210653-A HYPOTENSIVE AGENTS MERCK & CO., INC. (US) 1980-07-01 US disclosed
EP-0006614-A2 Pyridyl- and imidazopyridyloxypropanolamines, process for preparing the same and pharmaceutical compositions containing the same MERCK & CO. INC. (US) 1980-01-09 EP disclosed
US-4160036-A ADRENERGIC STIMULANTS ALLEN & HANBURYS LIMITED (GB) 1979-07-03 US disclosed
US-4123542-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS SYNTEX (U.S.A.) INC. (US) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339913-A1 SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS SARM1, SARNP, ADRM1 ALDH1A1 3991/4885PLAAT3 1471/4885PLAAT5 1656/4885
US-11753400-B2 D-amino acid oxidase inhibitors and therapeutic uses thereof DAO, DDO, DDC ALDH1A1 243/4885PLAAT3 2312/4885PLAAT5 3117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.