Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.50 |
| ▸ | CES1 | P23141 | 10/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533523 | 0.90 | FAAH (0.57) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9159433 | 0.82 | FAAH (0.58) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL10389160 | 0.80 | FAAH (0.62) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3440264 | 0.79 | LMNA (0.53) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL10388810 | 0.78 | FAAH (0.64) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1712961 | 0.77 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1712957 | 0.77 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL19181298 | 0.77 | ALDH1A1 (0.56) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1712722 | 0.77 | GAA (0.42) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL27410727 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604890-B2 | Compositions and methods for hydrocarbon functionalization | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160145188-A1 | COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION | UNITED STATES DEPARTMENT OF ENERGY | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145188-A1 | COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION | AHR, HMOX2, ALKBH3 | FAAH 184/4885CES1 2507/4885CES2 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.