Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 18/20 | 0.43 |
| ▸ | ACACA | Q13085 | 11/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026422 | 0.80 | NNMT (0.44) | ALDH1A1 | |
| SCHEMBL2201487 | 0.80 | NNMT (0.44) | ALDH1A1 | |
| SCHEMBL27681568 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ACACBACACA | |
| SCHEMBL30501667 | 0.77 | MAPT (0.49) | ACACB | |
| SCHEMBL1373919 | 0.75 | KMT2A (0.50) | ALDH1A1ACACBACACA | |
| SCHEMBL29636288 | 0.75 | ALDH1A1 (0.45) | ALDH1A1ACACBACACA | |
| SCHEMBL561514 | 0.75 | ALDH1A1 (0.45) | ALDH1A1ACACBACACA | |
| SCHEMBL28833451 | 0.75 | KDM4C (0.37) | — | |
| SCHEMBL1547410 | 0.75 | ACACB (0.53) | ALDH1A1ACACBACACA | |
| SCHEMBL5423751 | 0.73 | ACACB (0.46) | ALDH1A1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771357-B2 | ALXR agonist compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20160145249-A1 | ALXR AGONIST COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145249-A1 | ALXR AGONIST COMPOUND | MRGPRX2, MRGPRX1, MRGPRX4 | ALDH1A1 1112/4885ACACB 1806/4885ACACA 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.