Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201487 | 1.00 | NNMT (0.44) | NNMTCYP2A6MKNK1MKNK2KDM4E | |
| SCHEMBL21801745 | 0.85 | CA1 (0.41) | NNMTCYP2A6KDM4EMAPTLMNA | |
| SCHEMBL30501667 | 0.81 | MAPT (0.49) | MAPT | |
| SCHEMBL17766744 | 0.80 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL15563753 | 0.80 | KMT2A (0.42) | NNMTHSD17B1HSD17B2MAPTLMNA | |
| SCHEMBL3816388 | 0.79 | NNMT (0.48) | NNMTCYP2A6MKNK1MKNK2KDM4E | |
| SCHEMBL29525223 | 0.79 | NNMT (0.48) | NNMTCYP2A6MKNK1MKNK2KDM4E | |
| SCHEMBL38660384 | 0.78 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2891613 | 0.78 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL5424020 | 0.76 | KMT2A (0.42) | CHRNB2CHRNA4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388445-A | Indazole ether compound and preparation method and application thereof | 河北科技大学 | 2024-07-26 | — | — | CN | claimed |
| CN-118388445-A | Indazole ether compound and preparation method and application thereof | 河北科技大学 | 2024-07-26 | — | — | CN | disclosed |