Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | UQCRB | P14927 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267948 | 0.94 | LMNA (0.41) | LMNAENPP2TSHRALDH1A1NT5E | |
| SCHEMBL17768421 | 0.92 | LMNA (0.39) | LMNAENPP2TSHRALDH1A1NT5E | |
| SCHEMBL15004685 | 0.92 | LMNA (0.39) | LMNAENPP2TSHRALDH1A1NT5E | |
| SCHEMBL20379960 | 0.92 | LMNA (0.39) | LMNAENPP2TSHRALDH1A1NT5E | |
| Water SCHEMBL9870236 | 0.92 | LMNA (0.39) | LMNAENPP2TSHRALDH1A1NT5E | |
| Water SCHEMBL23522818 | 0.92 | LMNA (0.39) | LMNAENPP2TSHRALDH1A1NT5E | |
| Water SCHEMBL14977045 | 0.90 | LMNA (0.38) | LMNAENPP2TSHRALDH1A1NT5E | |
| SCHEMBL271881 | 0.88 | TSHR (0.46) | LMNAENPP2TSHRCA2ALDH1A1 | |
| SCHEMBL499291 | 0.85 | ESR1 (0.42) | LMNASENP1CA2ALDH1A1CA12 | |
| SCHEMBL10676586 | 0.84 | CA12 (0.44) | TSHRCA2ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891977-B1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR EV (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6107480-A | 5-(HYDROXYLATEDPHENYL) PORPHYRIN DERIVATIVES WHICH MAY BE COVALENTLY BONDED TO SPECIFIED POLYMERS VIA THE HYDROXYLATED PHENYL GROUP; USE AS PHOTOSENSITIZERS FOR THE CATALYTIC FORMATION OF SINGLET OXYGEN | DLR, DEUTSCHE ZENTRUM FUR LUFT UND RAUMFAHRT E.V. (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0891977-A1 | 5-(4-Hydroxyphenyl)-porphyrin derivatives as photosensitisers | DLR Deutsches Zentrum für Luft- und Raumfahrt e.V. (DE) | 1999-01-20 | — | — | EP | disclosed |