Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267948 | 0.94 | LMNA (0.41) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| SCHEMBL17768421 | 0.92 | LMNA (0.39) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| SCHEMBL15004685 | 0.92 | LMNA (0.39) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| Water SCHEMBL9870236 | 0.92 | LMNA (0.39) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| SCHEMBL20379960 | 0.92 | LMNA (0.39) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| Water SCHEMBL23522818 | 0.92 | LMNA (0.39) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| Water SCHEMBL14977045 | 0.90 | LMNA (0.38) | TSHRSMN1; SMN2POLBCYP2D6HDAC6 | |
| SCHEMBL7258220 | 0.88 | LMNA (0.53) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL10676586 | 0.87 | CA12 (0.44) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8167637 | 0.80 | ENPP2 (0.32) | TSHRENPP2LMNAALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133474-B2 | Porphyrin chelate compound that may be complexed with zinc, manganese, magnesium, iron or aluminum; capable of insertion into cell; zinc, calcium, mercury, cadmium, and lead analytes; determining shift in signal; medical diagnosis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-13 | — | — | US | disclosed |
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | CA2, SLC30A6, SLC39A3 | TSHR 4006/4885SMN1; SMN2 876/4885POLB 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.