Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | RORB | Q92753 | 3/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119850 | 0.88 | KMT2A (0.50) | MAPK14LMNAALOX15HSD17B10MAPK13 | |
| SCHEMBL17770569 | 0.85 | LMNA (0.60) | MAPK14LMNAALOX15HSD17B10MAPK13 | |
| SCHEMBL29658169 | 0.81 | CTSD (0.62) | LMNAALOX15HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL322168 | 0.81 | CTSD (0.62) | LMNAALOX15HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL27789892 | 0.79 | CTSD (0.60) | LMNAALOX15HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL1643544 | 0.79 | MAPK14 (0.59) | MAPK14LMNAALOX15HSD17B10MAPK13 | |
| SCHEMBL6652813 | 0.79 | MAPK14 (0.64) | MAPK14LMNAALOX15HSD17B10MAPK13 | |
| SCHEMBL15608370 | 0.79 | MAPK14 (0.50) | MAPK14LMNAMAPK13MAPK12MAPK11 | |
| SCHEMBL10370235 | 0.78 | ALDH1A1 (0.56) | MAPK14LMNAALOX15HSD17B10MAPK13 | |
| SCHEMBL1642408 | 0.77 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567026-A1 | 4,1-Benzoxazepin derivatives as squalene synthase inhibitors and their use in the treatment of hypercholesteremia and as fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |