Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16142548 | 0.86 | GRIN1 (0.33) | — | |
| SCHEMBL17771973 | 0.86 | DRD2 (0.32) | HTTKDM4EHPGDALDH1A1 | |
| SCHEMBL15412850 | 0.86 | PPARA (0.37) | SMN1; SMN2MGLLTSHRHTTKDM4E | |
| SCHEMBL10091819 | 0.86 | ACHE (0.33) | SMN1; SMN2CA2 | |
| SCHEMBL16142686 | 0.86 | GRIN1 (0.32) | — | |
| SCHEMBL19996327 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2NAAAHTTL3MBTL1KDM4E | |
| SCHEMBL16895225 | 0.85 | KMT2A (0.35) | SMN1; SMN2KDM4ECA2LMNACA12 | |
| SCHEMBL10091801 | 0.85 | ALDH1A1 (0.35) | SMN1; SMN2TSHRHTTKDM4ELMNA | |
| SCHEMBL10091808 | 0.85 | ALDH1A1 (0.33) | SMN1; SMN2TSHRHTTKDM4ELMNA | |
| SCHEMBL16142712 | 0.84 | DRD2 (0.33) | SMN1; SMN2HTTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067345-A1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | Siemens Healthcare Diagnostics Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2501681-B1 | ZWITTERION-CONTAINING ACRIDINIUM COMPOUNDS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2016-05-25 | — | — | EP | disclosed |