Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778332 | 0.92 | KIF11 (0.37) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17778350 | 0.91 | KIF11 (0.36) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17778487 | 0.90 | KIF11 (0.36) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17769566 | 0.89 | KIF11 (0.36) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17769729 | 0.89 | KIF11 (0.36) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17769731 | 0.89 | KIF11 (0.36) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL17778474 | 0.89 | KDM4E (0.38) | KIF11KDM4EUSP2LMNAALOX15 | |
| SCHEMBL17778477 | 0.89 | TRPV1 (0.35) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL20550338 | 0.85 | KIF18A (0.35) | KIF11KCNJ6KCNJ5KCNJ3KDM4E | |
| SCHEMBL20550336 | 0.85 | KIF18A (0.35) | KIF11KCNJ6KCNJ5KCNJ3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079712-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |