Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17768090 | 1.00 | RPS6KB1 (0.34) | RPS6KB1AKT1GPR52GRIN1GRIN2B | |
| SCHEMBL17778753 | 0.93 | GRIN1 (0.33) | RPS6KB1AKT1GRIN1GRIN2BUSP30 | |
| SCHEMBL17768177 | 0.93 | GRIN1 (0.33) | RPS6KB1AKT1GRIN1GRIN2BUSP30 | |
| SCHEMBL17768267 | 0.91 | CA2 (0.34) | RPS6KB1AKT1GRIN1GRIN2BUSP30 | |
| SCHEMBL17767983 | 0.89 | NPY2R (0.34) | RPS6KB1GRIN1GRIN2BKIF18AUSP30 | |
| SCHEMBL19689668 | 0.89 | GPR52 (0.41) | RPS6KB1AKT1GPR52KIF18ACA2 | |
| SCHEMBL17768071 | 0.87 | GPR52 (0.40) | RPS6KB1AKT1GPR52KIF18ACA2 | |
| SCHEMBL19706665 | 0.87 | GPR52 (0.40) | RPS6KB1AKT1GPR52KIF18ACA2 | |
| SCHEMBL17778793 | 0.86 | TRPV4 (0.34) | GRIN1GRIN2BKIF18AUSP30NPY2R | |
| SCHEMBL17767948 | 0.86 | TRPV4 (0.34) | GRIN1GRIN2BKIF18AUSP30NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |