Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.32 |
| ▸ | AKT1 | P31749 | 3/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 3/20 | 0.31 |
| ▸ | LIPC | P11150 | 3/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17768177 | 1.00 | GRIN1 (0.33) | GRIN1GRIN2BRPS6KB1AKT1CPT2 | |
| SCHEMBL17778754 | 0.93 | RPS6KB1 (0.34) | GRIN1GRIN2BRPS6KB1AKT1USP30 | |
| SCHEMBL17768090 | 0.93 | RPS6KB1 (0.34) | GRIN1GRIN2BRPS6KB1AKT1USP30 | |
| SCHEMBL17778226 | 0.90 | ALDH1A1 (0.33) | GRIN1GRIN2BCPT2CPT1ACPT1B | |
| SCHEMBL17768267 | 0.89 | CA2 (0.34) | GRIN1GRIN2BRPS6KB1AKT1CPT2 | |
| SCHEMBL17778738 | 0.89 | LIPG (0.36) | RPS6KB1AKT1RAF1BRAFCA2 | |
| SCHEMBL19689650 | 0.88 | GPR52 (0.35) | RPS6KB1AKT1STAT3CA2CA9 | |
| SCHEMBL17778685 | 0.84 | RPS6KB1 (0.33) | GRIN1GRIN2BRPS6KB1AKT1STAT3 | |
| SCHEMBL19670287 | 0.84 | PHGDH (0.38) | RPS6KB1LIPGKDM1AMAOAMAOB | |
| SCHEMBL16754334 | 0.83 | RAF1 (0.36) | GRIN1GRIN2BRPS6KB1AKT1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |