Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770420 | 0.87 | TMPRSS4 (0.46) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL17770333 | 0.86 | TMPRSS4 (0.46) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL17770334 | 0.84 | TMPRSS4 (0.46) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL30771735 | 0.82 | TMPRSS4 (0.70) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL14885885 | 0.82 | TMPRSS4 (0.70) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL19630873 | 0.81 | PDK1 (0.43) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL17770439 | 0.80 | HDAC1 (0.42) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL17770385 | 0.79 | GPR6 (0.42) | TMPRSS4KMT2AMEN1P2RX1PDK1 | |
| SCHEMBL19612092 | 0.78 | ALDH1A1 (0.47) | KMT2AMEN1CYP3A4ALDH1A1KDM4E | |
| SCHEMBL19630853 | 0.76 | P2RX7 (0.47) | TMPRSS4KMT2AMEN1GPR6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016081599-A1 | NOVEL MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-05-26 | — | — | WO | disclosed |