Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25953068 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL28083440 | 0.84 | CYP3A4 (0.43) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL4268288 | 0.83 | LMNA (0.40) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL17403685 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL30130307 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL2053675 | 0.81 | CYP3A4 (0.43) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL24721811 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL30036492 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL13816765 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPK1CYP3A4CA2TSHR | |
| SCHEMBL1777606 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPK1CYP3A4CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027596-B1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI SPA (IT) | 2018-11-21 | — | — | EP | disclosed |
| US-9776984-B2 | Compounds containing a pentalene unit and process for their preparation | ENI S.P.A. (IT) | 2017-10-03 | — | — | US | disclosed |
| US-9776984-B2 | Compounds containing a pentalene unit and process for their preparation | ENI S.P.A. (IT) | 2017-10-03 | — | — | US | disclosed |
| US-9776984-B2 | Compounds containing a pentalene unit and process for their preparation | ENI S.P.A. (IT) | 2017-10-03 | — | — | US | disclosed |
| EP-3027596-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.p.A. (IT) | 2016-06-08 | — | — | EP | disclosed |
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2016-03-31 | — | — | US | disclosed |
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2016-03-31 | — | — | US | disclosed |
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2016-03-31 | — | — | US | disclosed |
| WO-2015015368-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015015368-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | ENI S.P.A. (IT) | 2015-02-05 | — | — | WO | disclosed |
| WO-2008039529-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-04-03 | — | — | WO | disclosed |
| US-7208122-B2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-04-24 | — | — | US | disclosed |
| US-20070081921-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-04-12 | — | — | US | disclosed |
| US-20060120917-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-06-08 | — | — | US | disclosed |
| US-20060120923-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-06-08 | — | — | US | disclosed |
| EP-1080162-B1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INST TECHNOLOGY (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030178607-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-09-25 | — | — | US | disclosed |
| EP-1281744-A2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1080162-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999057222-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090371-A1 | COMPOUNDS CONTAINING A PENTALENE UNIT AND PROCESS FOR THEIR PREPARATION | C1S, SCLY, C1R | ALDH1A1 1691/4885MAPK1 1755/4885CYP3A4 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.