SCHEMBL4268288

SCHEMBL4268288

CCCCC(CC)COc1ccc2cc(Br)ccc2c1-c1c(OCC(CC)CCCC)ccc2cc(Br)ccc12

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.40
RXFP1 Q9HBX9 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPK1 P28482 2/20 0.38
CYP3A4 P08684 2/20 0.36
CA2 P00918 1/20 0.36
TSHR P16473 1/20 0.35
NCEH1 Q6PIU2 2/20 0.34
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
KDM1A O60341 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25987320 0.85 ALDH1A1 (0.38) LMNAMAPTALDH1A1MAPK1CYP3A4
SCHEMBL28700702 0.83 KDM1A (0.46) LMNASMN1; SMN2MAPTALDH1A1MAPK1
SCHEMBL1777917 0.83 ALDH1A1 (0.43) LMNASMN1; SMN2ALDH1A1MAPK1CYP3A4
SCHEMBL25953068 0.81 ALDH1A1 (0.43) LMNASMN1; SMN2MAPTALDH1A1MAPK1
SCHEMBL22110764 0.81 LMNA (0.46) LMNARXFP1SMN1; SMN2MAPTNCEH1
SCHEMBL4853806 0.79 SMN1; SMN2 (0.45) LMNARXFP1SMN1; SMN2MAPT
SCHEMBL23089940 0.77 ALDH1A1 (0.40) LMNARXFP1MAPTALDH1A1MAPK1
SCHEMBL29368388 0.77 ALDH1A1 (0.40) LMNARXFP1MAPTALDH1A1MAPK1
SCHEMBL26345931 0.77 LMNA (0.39) LMNARXFP1SMN1; SMN2MAPTNCEH1
SCHEMBL29675074 0.76 TSHR (0.46) LMNARXFP1SMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660450-A4 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIV LAVAL (CA) 2009-07-29 EP claimed
US-20070069197-A1 Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles UNIVERSITE LAVAL (CA) 2007-03-29 US claimed
JP-2007502251-A 2007-02-08 JP claimed
EP-1660450-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES Université Laval (CA) 2006-05-31 EP claimed
WO-2005016882-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIVERSITE LAVAL (CA) 2005-02-24 WO claimed
EP-4239035-A2 HIGH TRANSPARENCY ELECTROCHROMIC POLYMERS Ambilight, Inc. (KY) 2023-09-06 EP disclosed
US-20230250223-A1 HIGH TRANSPARENCY ELECTROCHROMIC POLYMERS AMBILIGHT INC. (KY) 2023-08-10 US disclosed
US-20230250223-A1 HIGH TRANSPARENCY ELECTROCHROMIC POLYMERS AMBILIGHT INC. (KY) 2023-08-10 US disclosed
EP-1660450-A4 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIV LAVAL (CA) 2009-07-29 EP disclosed
US-20070069197-A1 Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles UNIVERSITE LAVAL (CA) 2007-03-29 US disclosed
EP-1660450-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES Université Laval (CA) 2006-05-31 EP disclosed
WO-2005016882-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIVERSITE LAVAL (CA) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070069197-A1 Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles TELO2, DNMT1, DDT LMNA 3121/4885RXFP1 4360/4885SMN1; SMN2 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.