Styrene

Styrene

SCHEMBL1778002

C=Cc1ccccc1.Sc1ccccc1

nearest known ligand 0.74

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.74
TSHR P16473 1/20 0.74
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
MAOB P27338 2/20 0.38
CYP2A6 P11509 1/20 0.38
HDAC8 Q9BY41 4/20 0.37
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
MAPK1 P28482 2/20 0.32
NFE2L2 Q16236 1/20 0.32
CYP19A1 P11511 1/20 0.32
MAOA P21397 1/20 0.32
TRPA1 O75762 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8465847 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL140 0.86
Styrene SCHEMBL6258482 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL1226310 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL10892600 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL369036 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL9776790 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL4986035 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL11144289 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL8100955 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101501080-B Insulating layer, electronic component, field effect transistor, and polyvinylthiophenol MITSUBISHI CHEM CORP 2011-05-11 CN claimed
CN-101501080-A Insulating layer, electronic component, field effect transistor, and polyvinylthiophenol MITSUBISHI CHEM CORP (JP) 2009-08-05 CN claimed
CN-109071529-A pyrimidine compounds as JAK kinase inhibitors 施万生物制药研发IP有限责任公司 2018-12-21 CN disclosed
CN-104114608-B The manufacture method of polymerizable composition for optical material, its manufacture method and optical material MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2016-04-20 CN disclosed
CN-104114608-A Polymerizable composition for optical material, method for producing same, and method for producing optical material MITSUBISHI GAS CHEMICAL CO 2014-10-22 CN disclosed
US-7943639-B2 Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss PROXIMAGEN LIMITED (GB) 2011-05-17 US disclosed
CN-101501080-B Insulating layer, electronic component, field effect transistor, and polyvinylthiophenol MITSUBISHI CHEM CORP 2011-05-11 CN disclosed
CN-101501080-A Insulating layer, electronic component, field effect transistor, and polyvinylthiophenol MITSUBISHI CHEM CORP (JP) 2009-08-05 CN disclosed
CN-100472227-C Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens FUJI KASEI CO LTD (JP) 2009-03-25 CN disclosed
EP-1897881-A2 Compounds useful for the treatment of obesity, type II diabetes and CNS disorders Biovitrum AB (publ) (SE) 2008-03-12 EP disclosed
CN-101081845-A Substituted sulphone and sulphonamide compounds useful for the treatment of obesity, type II diabetes and cns disorders BIOVITRUM AB (SE) 2007-12-05 CN disclosed
CN-1662521-A Novel compounds useful for the treatment of obesity, type II diabetes and CNS disorders BIOVITRUM AB (SE) 2005-08-31 CN disclosed
CN-1657975-A Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens FUJI KASEI CO LTD (JP) 2005-08-24 CN disclosed
EP-1513828-A1 NEW COMPOUNDS USEFUL FOR THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS DISORDERS Biovitrum AB (SE) 2005-03-16 EP disclosed
US-20040024210-A1 New compounds PROXIMAGEN NEUROSCIENCE PLC (GB) 2004-02-05 US disclosed
CN-1471645-A Composition for optical material 三菱瓦斯化学株式会社 2004-01-28 CN disclosed
WO-2004000828-A1 NEW COMPOUNDS USEFUL FOR THE TREATMENT OF OBESITY, TYPE II DIABETES AND CNS DISORDERS BIOVITRUM AB (SE) 2003-12-31 WO disclosed
CN-1462290-A Polymerization regulator and composition for resin MITSUBISHI GAS CHEMICAL CO (JP) 2003-12-17 CN disclosed
CN-1093145-C Polymer polyol and flame retardant polyurethane resin and foam prepared therefrom MITSUI CHEMICALS INC (JP) 2002-10-23 CN disclosed
CN-1199059-A Polymer polyol and flame retardant polyurethane resin and foam prepared therefrom MITSUI CHEMICALS INC (JP) 1998-11-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024210-A1 New compounds SULT1E1, SULT2A1, SULT1A1 ALDH1A1 705/4885TSHR 1379/4885TDP1 3728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.