Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21411217 | 0.91 | EPHX1 (0.41) | KMT2AALDH1A1EPHX1HSD17B10HPGD | |
| SCHEMBL15416696 | 0.91 | EPHX1 (0.41) | KMT2AALDH1A1EPHX1HSD17B10HPGD | |
| SCHEMBL21629481 | 0.77 | LMNA (0.37) | — | |
| SCHEMBL12276428 | 0.76 | EPHX1 (0.46) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL26963280 | 0.75 | EPHX2 (0.33) | — | |
| SCHEMBL27125182 | 0.75 | EPHX2 (0.33) | — | |
| SCHEMBL6078871 | 0.75 | HSD11B1 (0.39) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL6080385 | 0.75 | HSD11B1 (0.39) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL20583811 | 0.74 | KDM4E (0.55) | MEN1KMT2ASTSGPR119 | |
| SCHEMBL29083228 | 0.74 | EPHX1 (0.45) | ALDH1A1MAPK1EPHX1HPGDSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872501-B1 | PYRIMIDINE PYRAZOLYL DERIVATIVES | ARES TRADING SA (CH) | 2016-06-01 | — | — | EP | disclosed |