Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 1.00 |
| ▸ | BRD4 | O60885 | 1/20 | 0.69 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.65 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613017 | 0.94 | TERT (0.88) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6614126 | 0.92 | TERT (1.00) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6612829 | 0.90 | TERT (0.86) | TERTCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL6613428 | 0.90 | TERT (0.81) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5280241 | 0.89 | TERT (0.80) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6613454 | 0.87 | TERT (1.00) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6802044 | 0.87 | TERT (0.77) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6612048 | 0.86 | TERT (0.88) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6614508 | 0.84 | TERT (0.73) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6616494 | 0.84 | TERT (0.72) | TERTBRD4CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814894-B1 | FLAVONOID COMPLEXES WITH CYCLODEXTRINS | MERCK PATENT GMBH (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-7943662-B2 | For skin/hair light protection; cosmetics | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20080112905-A1 | Flavonoid Complexes | MERCK PATENT GMBH (DE) | 2008-05-15 | — | — | US | disclosed |
| US-20080044364-A1 | Flavonoid Complexes | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2008-02-21 | — | — | US | disclosed |
| EP-1846429-A2 | FLAVONOID COMPLEXES COMPRISING CYCLODEXTRINES | Merck Patent GmbH (DE) | 2007-10-24 | — | — | EP | disclosed |
| EP-1814894-A2 | FLAVONOID COMPLEXES WITH CYCLODEXTRINS | Merck Patent GmbH (DE) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056297-A2 | FLAVONOID COMPLEXES COMPRISING CYCLODEXTRINES | MERCK PATENT GMBH (DE) | 2006-06-01 | — | — | WO | disclosed |
| WO-2006056308-A2 | FLAVONOID COMPLEXES WITH CYCLODEXTRINS | MERCK PATENT GMBH (DE) | 2006-06-01 | — | — | WO | disclosed |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080112905-A1 | Flavonoid Complexes | C9, C1R, CYC1 | TERT 1627/4885BRD4 2391/4885CSNK2A2 3724/4885 |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885BRD4 46/4885CSNK2A2 682/4885 |
| US-20080044364-A1 | Flavonoid Complexes | C1S, C1R, CYP4A11 | TERT 2772/4885BRD4 2569/4885CSNK2A2 3487/4885 |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885BRD4 47/4885CSNK2A2 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.