Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.77 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | IKBKB | O14920 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613428 | 0.92 | TERT (0.81) | TERTALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL6613017 | 0.88 | TERT (0.88) | TERTALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL6803222 | 0.88 | TERT (0.74) | TERTCYP1A1CYP1B1PABPC1ALDH1A1 | |
| SCHEMBL1778286 | 0.87 | TERT (1.00) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL6614126 | 0.85 | TERT (1.00) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL6797692 | 0.84 | CYP3A4 (0.66) | TERTCYP1A1CYP1B1PABPC1ALDH1A1 | |
| SCHEMBL6612829 | 0.82 | TERT (0.86) | TERTALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL6617685 | 0.82 | CSNK2A2 (0.74) | TERTALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL6614508 | 0.82 | TERT (0.73) | TERTCYP1A1CYP1B1ALDH1A1CYP3A4 | |
| SCHEMBL6804531 | 0.81 | TERT (0.81) | TERTALDH1A1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895344-B2 | Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof | EMORY UNIVERSITY (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895344-B2 | Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof | EMORY UNIVERSITY (US) | 2018-02-20 | — | — | US | disclosed |
| US-20110144196-A1 | TREATING VARIOUS DISORDERS WITH 7,8-DIHYDROXYFLAVONE AND DERIVATIVES THEREOF | EMORY UNIVERSITY (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144196-A1 | TREATING VARIOUS DISORDERS WITH 7,8-DIHYDROXYFLAVONE AND DERIVATIVES THEREOF | EMORY UNIVERSITY (US) | 2011-06-16 | — | — | US | disclosed |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885CYP1A1 2499/4885CYP1B1 2221/4885 |
| US-20110144196-A1 | TREATING VARIOUS DISORDERS WITH 7,8-DIHYDROXYFLAVONE AND DERIVATIVES THEREOF | NTRK2, BDNF, HTR7 | TERT 3053/4885CYP1A1 923/4885CYP1B1 931/4885 |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885CYP1A1 2558/4885CYP1B1 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.