P-Xylene

P-Xylene

SCHEMBL17784277

Cc1ccc(C)cc1.ClC(Cl)Cl

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.67
TDP1 Q9NUW8 1/20 0.67
ALDH1A1 P00352 4/20 0.47
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.44
ALOX12 P18054 1/20 0.44
CHRNA7 P36544 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2A6 P11509 2/20 0.40
IDO1 P14902 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL2589553 0.88 ACHE (0.61) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11301004 0.88 ACHE (0.61) ACHETDP1ALDH1A1CA2CA1
P-Cresol SCHEMBL11238776 0.84 ACHE (0.77) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11553864 0.82 ACHE (0.80) ACHETDP1ALDH1A1CA2CA1
Toluene SCHEMBL87982 0.82 ACHE (0.73) ACHETDP1ALDH1A1TSHRLMNA
Toluene SCHEMBL28398458 0.82 ACHE (0.73) ACHETDP1ALDH1A1TSHRLMNA
P-Xylene SCHEMBL460348 0.82 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11770184 0.82 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL11772917 0.82 ACHE (1.00) ACHETDP1ALDH1A1CA2CA1
P-Xylene SCHEMBL771 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287260-B2 Composite containing catalytic metal nanoparticles, and use for same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-05-14 US disclosed
US-20160152583-A1 COMPOSITE CONTAINING CATALYTIC METAL NANOPARTICLES, AND USE FOR SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-06-02 US disclosed
CN-102580082-B Inactived vaccine for poultry and preparation method thereof ZHAOQING DAHUANONG BIOLOG PHARMACEUTICAL CO LTD 2014-12-10 CN disclosed
CN-1017958-B INSECTICIDAL AND ACARICIDAL COMPOSITION CONTG. BENZOYLPHENYLUREAS OR SALTS THEREOF AND USE THEREOF CIBA GEIGY AG (CH) 1992-08-26 CN disclosed
CN-1051286-A Contain desinsection and the miticide composition and the application thereof of benzoyl phenylurea or its salt CIBA GEIGY AG (CH) 1991-05-15 CN disclosed
CN-1010945-B Preparation method of phenylhydantoin CIBA GEIGY AG (CH) 1990-12-26 CN disclosed
CN-85108238-A Preparation method of phenylhydantoin 1986-04-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152583-A1 COMPOSITE CONTAINING CATALYTIC METAL NANOPARTICLES, AND USE FOR SAME HPD, SND1, PGD ACHE 180/4885TDP1 2451/4885ALDH1A1 304/4885
US-10287260-B2 Composite containing catalytic metal nanoparticles, and use for same HPD, SND1, PGD ACHE 180/4885TDP1 2451/4885ALDH1A1 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.