SCHEMBL17784307

SCHEMBL17784307

C=C(C)C(=O)NCC(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.42
ATM Q13315 1/20 0.38
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TGFBR1 P36897 1/20 0.35
ALDH1A1 P00352 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ADORA2A P29274 1/20 0.32
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824323 0.83 THRB (0.35) THRBTGFBR1ALDH1A1MGAMGAA
SCHEMBL20337911 0.81 KMT2A (0.35) EPHX1ATMTHRBSMN1; SMN2TGFBR1
SCHEMBL9171383 0.81 TSHR (0.45) EPHX1THRBTGFBR1TSHR
SCHEMBL20337836 0.80 EPHX1 (0.39) EPHX1ATMMAPK1SMN1; SMN2ADORA2A
SCHEMBL136474 0.80 ALDH1A1 (0.39) THRBMAPK1SMN1; SMN2TGFBR1ALDH1A1
SCHEMBL10623417 0.80 EPHX1 (0.44) EPHX1ATMMAPK1SMN1; SMN2ADORA2A
SCHEMBL10314187 0.79 EPHX1 (0.46) EPHX1ATMMAPK1SMN1; SMN2ALDH1A1
SCHEMBL217295 0.79 EPHX1 (0.44) EPHX1THRBMAPK1TGFBR1ALDH1A1
SCHEMBL29043271 0.78 EPHX1 (0.43) EPHX1ATMMAPK1SMN1; SMN2ALDH1A1
SCHEMBL1197765 0.78 THRB (0.32) EPHX1ATMTHRBSMN1; SMN2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795399-B2 UV curable adhesion promoters based on functionalised polyvinyl alcohols MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11795399-B2 UV curable adhesion promoters based on functionalised polyvinyl alcohols MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
EP-3507343-B1 UV CURABLE ADHESION PROMOTERS BASED ON FUNCTIONALISED POLYVINYL ALCOHOLS MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
US-10793776-B2 Compositions comprising functionalized polyvinyl alcohol and nanocapsules containing a liquid crystalline medium MERCK PATENT GMBH (DE) 2020-10-06 US disclosed
EP-3467074-B1 COMPOSITIONS COMPRISING FUNCTIONALIZED POLYVINYL ALCOHOL AND NANOCAPSULES CONTAINING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-07-01 EP disclosed
US-20190321512-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2019-10-24 US disclosed
US-10363340-B2 Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof MCMASTER UNIVERSITY (CA) 2019-07-30 US disclosed
US-20190106627-A1 COMPOSITIONS COMPRISING FUNCTIONALIZED POLYVINYL ALCOHOL AND NANOCAPSULES CONTAINING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-04-11 US disclosed
EP-3467074-A1 COMPOSITIONS COMPRISING FUNCTIONALIZED POLYVINYL ALCOHOL AND NANOCAPSULES CONTAINING A LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2019-04-10 EP disclosed
WO-2018042026-A1 UV CURABLE ADHESION PROMOTERS BASED ON FUNCTIONALISED POLYVINYL ALCOHOLS MERCK PATENT GMBH (DE) 2018-03-08 WO disclosed
US-20160151535-A1 POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF MCMASTER UNIVERSITY (CA) 2016-06-02 US disclosed