Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337911 | 0.90 | KMT2A (0.35) | EPHX1ALDH1A1KMT2ATHRBGAA | |
| SCHEMBL1073008 | 0.83 | ALDH1A1 (0.34) | EPHX1ALDH1A1KMT2ADPP7ACHE | |
| SCHEMBL1547403 | 0.82 | KDM4E (0.50) | EPHX1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL1197765 | 0.82 | THRB (0.32) | EPHX1ALDH1A1KMT2ATHRBGAA | |
| SCHEMBL6062528 | 0.79 | EPHX1 (0.48) | EPHX1ALDH1A1KMT2ADPP7ACHE | |
| SCHEMBL3717942 | 0.79 | EPHX1 (0.48) | EPHX1KMT2ADPP7ACHEMEN1 | |
| SCHEMBL17784307 | 0.79 | EPHX1 (0.42) | EPHX1ALDH1A1KMT2ATHRBMEN1 | |
| SCHEMBL9137813 | 0.78 | EPHX1 (0.44) | EPHX1ACHETHRB | |
| SCHEMBL28346305 | 0.77 | KDM4E (0.37) | ALDH1A1KMT2ADPP7ACHEMEN1 | |
| SCHEMBL25557372 | 0.77 | ANPEP (0.41) | EPHX1ALDH1A1DPP7GAATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1675252-B | Macromer combination and preparation method thereof | JOHNSON & JOHNSON VISION CARE | 2010-05-12 | — | — | CN | claimed |
| EP-1534759-B1 | MACROMER FORMING CATALYSTS | JOHNSON & JOHNSON VISION CARE (US) | 2009-09-09 | — | — | EP | claimed |
| US-7429623-B2 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-09-30 | — | — | US | claimed |
| US-20060004119-A1 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. | 2006-01-05 | — | — | US | claimed |
| US-6936641-B2 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-08-30 | — | — | US | claimed |
| EP-1534759-A1 | MACROMER FORMING CATALYSTS | Johnson & Johnson Vision Care, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| US-20040002556-A1 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. | 2004-01-01 | — | — | US | claimed |
| WO-2004000888-A1 | MACROMER FORMING CATALYSTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| US-8088313-B2 | Producing contact lenses, using two half molds, and at least one mask, feeding a polymerizable prepolymer dissolved in a solvent, irradiating to crosslink and copolymerize the polyvinyl alcohol derivatives; crosslink at target area | NOVARTIS AG (CH) | 2012-01-03 | — | — | US | disclosed |
| CN-1675252-B | Macromer combination and preparation method thereof | JOHNSON & JOHNSON VISION CARE | 2010-05-12 | — | — | CN | disclosed |
| EP-1534759-B1 | MACROMER FORMING CATALYSTS | JOHNSON & JOHNSON VISION CARE (US) | 2009-09-09 | — | — | EP | disclosed |
| US-7429623-B2 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20060004119-A1 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. | 2006-01-05 | — | — | US | disclosed |
| US-6936641-B2 | Macromer forming catalysts | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| WO-1996024074-A1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |
| US-5508317-A | CONTACT LENSES | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| CN-1108999-A | A process and device for the manufacture of mouldings and mouldings manufactured in accordance with that process | CIBA GEIGY AG (CH) | 1995-09-27 | — | — | CN | disclosed |
| EP-0641806-A2 | Photocrosslinked polymers | CIBA-GEIGY AG (CH) | 1995-03-08 | — | — | EP | disclosed |
| EP-0637491-A1 | Process and device for the production of moulded objects as well as objects produced by this process | CIBA-GEIGY AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| EP-0637490-A1 | Process and device for production of moulded parts as well as the so manufactured parts | CIBA-GEIGY AG (CH) | 1995-02-08 | — | — | EP | disclosed |