Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672302 | 0.84 | CNR1 (0.49) | CNR1PPARGFNTAFNTBSMN1; SMN2 | |
| SCHEMBL1780538 | 0.82 | CNR1 (0.47) | CNR1FNTAFNTBMTNR1AADORA2A | |
| SCHEMBL1778456 | 0.79 | MTNR1A (0.66) | MTNR1A | |
| SCHEMBL29868708 | 0.79 | MTNR1A (0.66) | MTNR1A | |
| SCHEMBL857278 | 0.76 | CCNB2 (0.68) | CNR1FNTAFNTBADORA2AADORA1 | |
| SCHEMBL1778446 | 0.75 | HTR6 (0.49) | CNR1FNTAFNTBSMN1; SMN2ADORA2A | |
| SCHEMBL8140328 | 0.73 | HTR6 (0.64) | CNR1MTNR1AADORA2AADORA1 | |
| SCHEMBL1777136 | 0.72 | CLK1 (0.49) | CNR1FNTAFNTBADORA2AADORA1 | |
| SCHEMBL1779054 | 0.72 | CCNB2 (0.48) | CNR1FNTAFNTBMTNR1AADORA2A | |
| SCHEMBL6668264 | 0.72 | FNTA (0.78) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943616-B2 | Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-17 | — | — | US | disclosed |