Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353125 | 0.76 | — | — | |
| SCHEMBL15824349 | 0.72 | — | — | |
| SCHEMBL5926320 | 0.68 | ADRA2B (0.34) | NPSR1 | |
| SCHEMBL10774523 | 0.64 | GABRA1 (0.32) | — | |
| SCHEMBL5358925 | 0.63 | — | — | |
| SCHEMBL27633317 | 0.62 | ALDH1A1 (0.37) | NPSR1 | |
| SCHEMBL7829376 | 0.61 | GABRA1 (0.30) | — | |
| SCHEMBL13281358 | 0.61 | GABRA1 (0.38) | — | |
| SCHEMBL16637908 | 0.60 | — | — | |
| SCHEMBL29281370 | 0.60 | ALDH1A1 (0.32) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943618-B2 | Btk protein kinase inhibitors | ROCHE PALO ALTO LLC (US) | 2011-05-17 | — | — | US | claimed |