SCHEMBL17791124

SCHEMBL17791124

CCOc1ccc(-c2ccc(-c3ccc(C)cc3)c(F)c2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR2 P21802 2/20 0.41
▸ FGFR1 P11362 1/20 0.41
▸ ADORA3 P0DMS8 1/20 0.40
▸ CTSA P10619 1/20 0.38
▸ PTGS2 P35354 6/20 0.38
▸ PDE3B Q13370 1/20 0.38
▸ PDE3A Q14432 1/20 0.38
▸ PTPRC P08575 1/20 0.38
▸ NAAA Q02083 1/20 0.37
▸ PTGS1 P23219 2/20 0.37
▸ ALOX5AP P20292 1/20 0.37
▸ FEN1 P39748 1/20 0.37
▸ MAPT P10636 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ HPGD P15428 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15119769 0.91 ADORA3 (0.43) FGFR2FGFR1ADORA3PTGS2PTPRC
SCHEMBL17791127 0.90 ALOX5AP (0.40) FGFR2FGFR1ADORA3CTSAPDE3B
SCHEMBL16771252 0.89 ADORA3 (0.42) FGFR2FGFR1ADORA3PTGS2PTPRC
SCHEMBL17791125 0.89 PPARD (0.41) PDE3BPDE3AALOX5APFEN1KDM4E
SCHEMBL21609904 0.88 FGFR2 (0.44) FGFR2FGFR1ADORA3PTGS2PTPRC
SCHEMBL20010658 0.88 FGFR2 (0.41) FGFR2FGFR1ADORA3PTGS2PTPRC
SCHEMBL17791128 0.88 PPARD (0.40) PDE3BPDE3AALOX5APFEN1MAPT
SCHEMBL17791126 0.87 FGFR2 (0.41) FGFR2FGFR1PTGS2PTPRCNAAA
SCHEMBL17791131 0.87 RARB (0.42) ALOX5APFEN1MAPTALDH1A1NPSR1
SCHEMBL16855917 0.86 FGFR2 (0.46) FGFR2FGFR1PTGS2PTPRCNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333428-A1 LIQUID CRYSTAL DISPLAY DEVICE Sharp Display Technology Corporation (JP) 2023-10-19 — — US disclosed
WO-2021253624-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY 石家庄诚志永华显示材料有限公司 2021-12-23 — — WO disclosed
US-10400169-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-09-03 — — US disclosed
US-10208251-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-02-19 — — US disclosed
US-20180086980-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-03-29 — — US disclosed
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-02-01 — — US disclosed
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-02-01 — — US disclosed
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-16 — — US disclosed
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044438-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885
US-20180030350-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885
US-10400169-B2 Liquid-crystalline medium VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885
US-20170044437-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885
US-10208251-B2 Liquid-crystalline medium VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885
US-20160152587-A1 LIQUID-CRYSTALLINE MEDIUM VIM, COL2A1, COL1A1 FGFR2 386/4885FGFR1 70/4885ADORA3 2642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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