SCHEMBL17791502

SCHEMBL17791502

CC(=O)/N=N/C=C1C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
GPR35 Q9HC97 1/20 0.39
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
CES2 O00748 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
CES1 P23141 1/20 0.34
MPI P34949 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17791503 0.78 LMNA (0.35) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL17791501 0.77 POLB (0.36) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL16133489 0.77 PTGS2 (0.36) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL17791507 0.77 NPC1 (0.33) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL17794334 0.75 KMT2A (0.40) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL22139551 0.73 TDP1 (0.40) NPC1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL16133488 0.73 POLB (0.37) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL4456724 0.73 ATM (0.41) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL16606380 0.72 TRPA1 (0.41) ATMNPC1KMT2AGPR35ALDH1A1
SCHEMBL24543911 0.71 ATM (0.35) ATMNPC1KMT2AGPR35ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10884346-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-01-05 US disclosed
US-20200201199-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-06-25 US disclosed
US-9783491-B2 Quinone derivative and electrophotographic photosensitive member KYOCERA DOCUMENTS SOLUTIONS INC. (JP) 2017-10-10 US disclosed
US-9783491-B2 Quinone derivative and electrophotographic photosensitive member KYOCERA DOCUMENTS SOLUTIONS INC. (JP) 2017-10-10 US disclosed
US-20160152556-A1 QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-06-02 US disclosed
US-20160152556-A1 QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152556-A1 QUINONE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER KEAP1, RAD54L, ATXN2L ATM 2359/4885NPC1 3820/4885KMT2A 2994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.