Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PTAFR | P25105 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999954 | 0.91 | FPR2 (0.34) | SLC6A2SLC6A4SLC6A3PDE5AHTR2C | |
| SCHEMBL10303353 | 0.85 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3PDE5APTAFR | |
| SCHEMBL12907908 | 0.82 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3PDE5AHTR2C | |
| SCHEMBL13000737 | 0.81 | TDP2 (0.35) | SLC6A2SLC6A4SLC6A3HTR2CALDH1A1 | |
| SCHEMBL16852462 | 0.80 | — | — | |
| SCHEMBL12759103 | 0.80 | — | — | |
| SCHEMBL19818330 | 0.80 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3PDE5AHTR2A | |
| SCHEMBL10303285 | 0.78 | KDM1A (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13262953 | 0.77 | FPR2 (0.33) | SLC6A2SLC6A4SLC6A3PDE5A | |
| SCHEMBL10303308 | 0.77 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714381-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-25 | — | — | US | disclosed |
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044436-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20160152587-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | SLC6A2 4606/4885SLC6A4 3961/4885SLC6A3 3477/4885 |
| US-20170044437-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | SLC6A2 4606/4885SLC6A4 3961/4885SLC6A3 3477/4885 |
| US-20160152587-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | SLC6A2 4606/4885SLC6A4 3961/4885SLC6A3 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.